Stem Cell–Conditioned Growth Factor Technology
What We Offer
Biotuned Health distributes Invitrx’s FDA-registered, cGMP-manufactured P.E.M.
formulations for professional cosmetic and regenerative use.
P.E.M.
(Human Cord Blood / Mesenchymal Stem Cell Conditioned Media)
Highly concentrated bioactive solution for skin rejuvenation and scalp restoration.
P.E.M.
(Human Foreskin Fibroblast Conditioned Media)
Fibroblast-derived version that enhances collagen synthesis, elasticity, and tissue repair.
P.E.M. (Polypeptide Enriched Media)
Polypeptide Enriched Media (P.E.M.) is a stem cell–conditioned media that contains over 380 natural bioactive molecules, including peptides, cytokines, and growth factors. It captures the regenerative ‘language’ of stem cells—delivering complex signals that restore, protect, and rejuvenate skin and hair.
P.E.M. is an acellular product—meaning it does not contain living cells—but carries the benefits of cell communication. It stimulates collagen production, promotes elasticity, and supports overall skin and scalp health.
What Is P.E.M.?
P.E.M. is produced by cultivating stem cells in a controlled environment and collecting the secreted media. This bioactive medium, rich in peptides and growth factors, mimics the regenerative microenvironment that naturally occurs in youthful skin.
Technical Highlights
Contains over 380 verified growth factors, cytokines, and extracellular vesicles
Up to 92% concentration of stem cell–conditioned media
Clinically demonstrated non-cytotoxic and stable for 2 years at 4–5°C
Produced in FDA-registered, cGMP-certified laboratories
Key Benefits
Polypeptide-enriched media offer benefits in cellular processes like enhanced collagen and elastin production, which improves skin firmness and elasticity.
For Licensed Professionals
P.E.M. formulations are designed for professional dermatologic and cosmetic applications. Licensed clinicians, medspas, and product developers may request product samples and partnership opportunities through Biotuned Health.